Week 10 picks: upsets and score predictions, matchup breakdowns for each game

What's in store for the Falcons' Colts rivalry in Berlin?Will New England's six-game winning streak end in Tampa?Who takes the heavyweight matchup between the Eagles and Packers on Monday night?Check out the week 10 game picks!

editors Ali Bhanpuri, Tom Blair, Brooke Cersosimo, Gennaro Filice and Dan Parr will predict the winner of every match in the 2025 season using the unbeatable combination of football analysis and excessive punctuation.Check out their Week 10 picks below.

| Ali | 91-43 (67,9 %) | 67-68 (49,6 %) | 72-63 (53,3 %) | 6-2 (75,0 %) | 6-3 (66,7 %) |

|Tiyi |87-47 (64,9%) |15 700 % (44,3 %) |12-15 (44,3%) |

|and |93-41 (69.4%) |64-71 (47.4%) |68-67 (50.4%) |0-1 (0.0%) |1-1 (50.0%) |

Gennaro |89-45 (66.4%) |74-61 (54.8%) |67-68 (49.6%) |3-9 (25.0%) |8-6 (57.1%) |

|I-TOM |91-43 (67.9%) |I-65-70 (48.1%) |59-76 (43.7%) |0-1 (0.0%) |2-3 (40.0%) |

|Event |19-61 (76.3%) |18-15 (45.5%) |7-9 (56.3%) |

Lines provided by DraftKings are locked as of 1:00 p.m.ET on Thursday, November 6.

SUNDAY, NOV. 9

- WHERE: Olympic Stadium (Berlin, Germany)

- When: Until 9:30 p.m

- MONEYLINE : Faucons +270 |Colts -340

- Translation spread: Colts -6.5 |O / h: 48.5

|Ali |Brooke |and |Genaro |Tom |

Colts 27-21 |

I-Colts 27-23 |

Colts 27-21 |

Foals 33-19 |

Colts 28-21 |

Why Dan chose the Falcons: Before they enjoy the AFC South leaders, they have a tough task ahead of them.offense against a top-ranked defense.If the worst version of Daniel Jones shows up in Week 2, Atlanta has a great chance to snap a three-game losing streak.However, the study notes that dating back to 2007, 10 of the 10 offenses won against top-ranked defenses.THE COLTERS WILL WIN WELL AT GUARD JONAH TALLOR, GUARD JONATHAN TYCOR, AND GUARDS AT POWER.Raheed played Morris a few times.India must bounce back.

- Location: Bank of America (Charlotte, North Carolina)

-I-cum: 1:00 a.m.et | i-fox '

- MONEY LINE: Saints +200 |Panthers -245

- SPREAD: Panthers -5.5 |O/U: 39.5

|Ali |Brooke |Epi |Gennaro |Tom |

Panthers 24-18 |

Panthers 24-16 |

Panthers 23-17 |

I-Panthers 24-14 |

Panthers 23-16 |

Why Brooks picked the Panthers: The Panthers, who have won four of their last five, including last week's road sweep of the Packers, have a hot game led by Rico Dowdle.The veteran quarterback has been incredible in his three starts, averaging 173 rushing yards and 204.7 scrimmage yards (all wins) in those games.Unlikely to lose, especially against a New Orleans defense that allowed the sixth-most rushing yards to a running back in 2025. Expect another big breakout from the Panthers' breakout star.Bryce Young has been making timely plays of late, leading a nine-play, 40-yard drive to set up the game-winning field goal last week.Hard to believe the 1-8 Saints can turn things around right now, especially on offense.They scored just 10 runs and hit a season-low .224 in Tyler Shoff's first career hit last week.was power.They just traded Rasheed Shahid, who was five of 15 for Schauch in that loss. Carolina is capable of taking care of business and putting more pressure on the division-leading Bucks.

- VENUE: Soldier Field (Chicago)

- When: 1:00 p.m.ET |Fox

- MONEYLINE: Giants +180 |Bears -218

- Spred: Bears -4.5 | T / l: 46.5

|But |Brooke |I |Gennaro |Tom |

All 30-24 |

Bears 26-20 |

Bears 27-22 |

Been 27-23 |

To 27-21 |:::

Why Ali chose the Bears: The Giants have been struggling since they upset the Eagles in Week 6, dropping at least 33 points and more than 140 places in their last game.What’s worse for the G-Men men this weekend as they face two league attacks in a hurry (No. 1 since Week 6).As the Big Blue looks more and more dramatic, Chicago has found new life behind the reviving game.The fall of the epic one year ago turned into the fall epic of 2025 by the Bears, who found themselves on the right side of a double-clawed claw on their last four games.But Chicago is far from a complete package, with its standings close to the bottom of the league in a number of key categories, including points per game (28.4) and pitch per game (26).The unit’s only bright spot is maintained.The Bears have forced a high of 19 species this year.If the defense can steal one or two more assets on Sunday, I have faith in Ben Johnson and the ground game to succeed against the Giants.Expect more points and maybe some snow (!) In this NFC fight.

- Location: NRG Stadium (Houston)

- Bila: 1:00 p.m. et |CBS

- Moneyline: Jaguars -130 | Texans +110

- Spread: Jaguar -1.5 |O/U: 37.5

Jaguar 19-17 |

Texans 19-17 |

Texans 20-17 |

Texans 17-16 |

Texts 22-14

Why Tom picked the Texans: Because I spent too much time thinking about this drive and how much I trust Trevor Lawrence and Jacksonville's inconsistent offense to hold up against Houston's terrible defense.Lawrence is averaging less than 7 yards per throw for the first time since his rookie season, and I'm not sure Jacoby Meyers is going to start in his first game with the team, especially Derek Stingley.Jr.hanging around there.I was ready to explain why, despite these factors working in favor of the home team, I couldn't take the Texans because of backup QB Davis Mills, who C.J. will start for Stroud (concussion), thus limiting Houston's offense to the point that the Jaguars could win a road game with a blitz or two from Lawrence.After all, Lawrence already helped the Texans to a 17-10 win in Week 3 in Jacksonville, despite having the eighth-lowest passer rating of his career (56.5) in that game.But the Jags' defense has been soft since then.It was, and Houston got stronger, and I can't shake the feeling that Lawrence and Co.will struggle to hold against the Heat.

- DOVE: Hard Rock Stadium (Miami Gardens, Florida)

- When: 1:00 p.mCBS

- MONEYLINE: bills -470 |dolphins +360

- Spread: Bills -9.5 |O/U: 50.5

Accounts 30-20 |

Notes 28-21 |

Bills 30-20 |

Bills 35-16 |

Account 31-20 |

Why Gennaro picked the Bills: Because I picked Buffalo to make Super Bowl LX, and Super Bowl teams don't lose this game.More specifically, Sean McDermott's Bills don't lose this game.The franchise has a 16-2 record against Miami since the head coach took over in 2017, recording its most recent victory a few months ago in Buffalo.That Thursday night game was extremely competitive, but given the positions of these two teams respectively, it's hard to imagine a tighter contest this time around.In fact, the Dolphins had just parted ways with their general manager, forcing the head coach and quarterback to talk about job security.Meanwhile, up north, the Bills had overcome the AFC's superpowers, allowing head coaches and quarterbacks to clash with colleagues.On the field, the fickle Fins have scored six points in two of the last three weeks, and the Bills' top-ranked offense is coming off a Week 7 bye.Now, the addition of James Cook to the injury report on Wednesday is a foot/ankle case worth monitoring, as he plays a key role in Buffalo's impressively efficient ground game.That said, Kansas City's Josh Allen suffered a surgical tear through the air, so I think the reigning MVP will be fine if asked to carry more of the offensive load on Sunday, especially against this injury-riddled Miami secondary.

- Location: U.S.Bank Stadium (Minneapolis)

- When?1:00 p.m. ET |Fox:

- Geld card: - Ravens -225 |Viking + +185

- RIDE: RaveS -4.5 |O/U: 49.5

|Ali |Block |and Gẹnnaro |

Levels 28-23 |

Ravens 26-23 |

Ravens 28-23 |

Ravens 30-21 |

Brave Brock took the wall: Vicki screamed at the rock.Odds: Three times Minota won, it made the NFC Championship Game.In the four seasons he lost, his head teacher was fired.Right now, I can't see any scenario where Kevin O'Connell is looking for work anytime soon.McCarthy is playing well to share the field.McCarthy has been moved to quarterback and has been working back since week 6. Good news for the young, only backles, so he needs to work in the pocket and find a tight end.Ginl launched and used the FOF gif to make a great announcement.Of course, that's overkill, that's a lot of different MVP's in the old MVP is a lot different than the last thing.Is it the style of the minister, blitz-round games passing Bentorre?

- Where: MetLife Stadium (East Rutherford, NJ)

- WHEN: 1:00 PM BUT |CBS

- POINTS: Browns -130 |Jets +110

- EXTENSION: Browns -1.5 |O/U: 37.5

|Ali |Brooke |Eta |Gennaro |Tom |

Browns 21-18 |

Browns 17-13 |

Browns 21-17 |

Browns 16-13 |

Browns 20-17 |

Why Tom got brown: I love it, I can't believe it.In a few ways, the logic favors Cleveland last week, Delton Gabriel in Week 7, and now the redshirt kit inspires more confidence.Of course, the Jets give both of them a bit of confidence once the EPA is done.Back to where he came from three weeks ago Regardless of who starts QB Green, the Browns will be 500 yards from Justin Park, the Coast's first winner.The track setup made me a little nervous, and the level of Carson Schwesing's ankles made me a little nervous.confirmed (MyS Garrett, DenzeT, DENINER TARD), although I would send them two (Queenen Gardner, Queenen Gardner, Queenen Gardner

- O fea: Raymond James Stadium (TamA, Florida)

- to: 1:00 p.sc.E |Cbs

- money line: Patriots +124 |Buccaneers -148

- spread: Buccaneers -2.5 |O / U: 48.5

|Ali |Brooke ||Gennaro |Tom |

Patriots 24-23 |

Bucaners 25-22 |

Patriots 23-21 |

Buccanersers 28-23 |

Buccaneers 25-22 |

Why Dan keeps people watching: In a battle between two teams that have easy battles, it's hard for me to go against a team that is at home and yolo.The off week gave the buccaneers a chance to rest.Still, they are still far from full strength due to injuries and mayfield hasn't been there since the break.Meanwhile, the hosts have won six straight games and made history on both sides.Ball.Despite the pass-and-down defense, New England did not allow a return to reach 50 seasons in the game, the longest season passed by a team in the season of the season in the ship.I respect Tampa Bay's resilience, but I'm not sure they have a healthy defense to win this.

Where: Lumen Field (Seattle)

- When: 16: 05. et |cbs

- Moneyline: Cardinals +245 |Seahawks -305

- Spread: Seahawks -6.5 |O/U: 45.5

|||Brookooke |On |Gennaro |Tom |

Seahawks 23-17 |

Seahawks 30-20 |

Skyawks 26-21 |

Seahawks 24-20 |

Coaster 26-19 |

Why Gennaro chose the Seahawks: Seattle just flew across the country and put the brakes on Washington in the first round, so it's easy to think the Seahawks will come back to this place and wipe out a sub-.500 foe.Arizona ended the night with a 10-point lead in Dallas.The Cards' offense has been powered by Jacoby Brissett over the past three games, and he will now be on the job for at least four weeks while Kyler Murray will be injured on Wednesday.However, if we look back at the transfer game, Seattle has been a oil-fueled machine this season, with Sam Darnold and Jaxon Smith-Ngiba quickly vowing to be the driving force behind an impressive result.Now that the Seahawks just sold Rasheed Shaheed, they're back in the bullpen with throwing coordinator Clint Cubint.Remember those two firecrackers before Shahid escaped danger in New Orleans early last season?So, it's easy, easy to imagine getting beat up, especially considering Seattle's defense was the most controversial in the game.But again, these Cardinals have been close against everyone -- including the Eagles' three-point trip to Arizona State in Week 4.I saw the same results on Sunday.

- NOT: Levi's Stadium (Santa Clara, CA)

- WHEN: 4:25 PM ET |NOV

- MONEY LINE: Rams -225 |49ers +185

- LAYOUT: Rams -4.5 |O/U: 49.5

|Ali |Brooke |En |Gennaro |Tom |

Brave 26-22 |

49ers 24-23 |

Rams 27-21 |

Rams 27-19 |

Rams 28-21 |

Why Tom chose Ram: Because we're going to be normal, okay, guys?I know the 49ers have somehow turned their winning record around — including a 3-0 lead in the NFC West — despite losing basically every key player at one point.And I know that each of the last five games in this series has been decided by one point or lessBut that doesn't come down to some random shot or dunk or head or dunked coachThe Twins are a solid, healthy group in control of the game and have one of the second-ranked defenses in the EPL.Meanwhile, the NINERS mostly run away from pass rushers, very few on pass rushers, and McConnell ranks fourth on the team with 27 interceptions.San Francisco's Juju is at least this weekend, and the team that needs to win will win.

- Where: Northwest Stadium (Gandover, Md.)

- ha: 4:25 p.m.And |Fox

- Moneyline: Lion-470 |Commander +360

- Dido: Lines -7.5 |o/u: 49.5

|Ali |Used |VA |GennaroTom |

Lions 31-17 |

Levy 32-20 |

Levy 24-16 |

Lions 31-9 |

Lions 28-20

Why Ali chose the Lions: The Chiefs enter this weekend on the heels of one of the biggest demos in franchise history this weekend.Washington's defense added insult to injury as the team struggled on Sunday night, particularly because of the Sea-10's 31-yard offense.Detroit's offense is also low and in a mini slump.But let's let Chiefs Jared Goff and co.below mid season level... can they also count on the marcus marcus brand?I think it is possible.the longest active streak in the NFL since he didn't miss a game in more than three years.Not only do the Lions consistently lead DC, but they tend to sign people after averaging 16.6 points and punish people after scoring 16.6.

- Where: SoFi Stadium (Inglewood, California)

- When: 20:20 and NBC, Universo

- Moneyline: Steelers +136 | pengecas -162

- Ifunni: Compargers -3 | O / U: 45.5

| Ali | brooke | Gennaro | Tom |

Tilers 23-20 |

Thief 24-22 |

Steelers 24-20 |

Steelers 21-19

Charger 24-20 |

WHY Brooke chose the Pilgrims: Aaron Rodger's first job at the Sofi Stadium on Sunday, who we travel well?But most of the interest in this contest will be on the game where Rodger is on the field: Pittsburgh based on the offense of Los Angeles that has a very bad line that has a bad line.he helps, but time will tell how much he does to the offensive unit.The lack of Alt is huge, while Herbert already has the QBS with the most pressure in the nfl.Sigran Signal-Caller took 28 sacks (Third-Third) and 80 QB hits (Most) It could be bad if Herbert is stable.We should also know that Mike Tomlin said Jalen Ramsey will continue to work on the defense after week 9. People's mistake so we don't doubt - true, is this game?What?- But it seems to find something with Rodger Down.After all, he scored 95-Plus Plaitger in his six games.The Chiefs defense isn't great though, ranking sixth in all-time yards allowed, third in punting and second in sacks, so don't expect Pittsburgh to get away with it.

Mane, Nov. 10

- Gdje: Lambeau Field (Green Bay, Wis.)

-Kub: 8: 15 BJET |ABC, ESPN, ESPN2, ESPN Deptis

- Moneyline: Eagles +114 |Package -135

- Distribution: packer -2.5 |O/U: 45.5

,AliBrooke |en |GennaroTom

Eagles 27-24 |

Eagles 26-23 |

Hems 23-22 |

Hems 27-20 |

Pakirke 24-21 |

Why Dan chose the Eagles: The last time we saw Jordan like playing against Philadelphia, he threw three interceptions in a game that ended the Packers' season.Now he wants to avoid a loss without his most important weapon, Tucker Craft, who was starved in Green Bay's upset loss to the Panthers.I don't like the timing of this game for the first-place team in the NFC North.He has been filled in and has not lost his regular-season designation since Nick Sirianni was hired as head coach in 2021. Meanwhile, we have seen some cracks appear in the Packers' return, as the team has allowed 5 yards per game over the past two weeks.The group's inconsistency this season makes me unsure what to expect from them.I'm leaning slightly in favor of Philly given the circumstances.

- WHERE: Mile High Empowerment Field (Denver)

- When: 8:15 PM ET |Prime Video

- Money line-robbers +390 |Broncos -520

- Yada: Broncos -9.5 O / U: 42.5

|But |Brotolow |I|GennaroTom |

Broncos 27-18 |

Broncos 26-18 |

Broncos 27-17 |

Broncos 23-20 |

Broncos 26-16 |

Why Genno attacked the Broncos: As a shortstop between the division runners, more could be imposed than meets the eye.This time, two of the most interesting people in the Island game come to be selected for the second year: the 12 chooses what is in the last two fields) and the athletes who take care of business (13).They both do well in year one - the second carers after Jayden, wherever it makes him not leave in twenty years.happen.But the knee injury sustained during the Las Vegas Players Open in New England immediately (and later spelled) the end for Starr.Finally, it was cured last week, the handlers will return to the list and exactly one of the common methods of the season: 13 rooms 12, 12 yards and three points.On the other hand, the chaos of Knicks was different.Basically, he'll go in the top three (see: 81.7 rookie rating, 10: 5 TD-to-ificafio, 7 blocked drives, game win).With that in mind, this is one TNF text that happens to me: Bauer says good and the Broncos' winning season in week six.

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